Details for gene set NCI_CLASS I PI3K SIGNALING EVENTS[GSEA]

Table: GSEA Results Summary

Dataset	set02_BT_ATM_minus_versus_ATM_plus
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	NCI_CLASS I PI3K SIGNALING EVENTS
Enrichment Score (ES)	0.44207335
Normalized Enrichment Score (NES)	2.03267
Nominal p-value	0.0
FDR q-value	0.0045683943
FWER p-Value	0.072

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	EGR3	3	25.122	0.0278	Yes
2	LCK	20	19.234	0.0485	Yes
3	TNFRSF1A	22	18.882	0.0695	Yes
4	EGR2	41	16.374	0.0869	Yes
5	ITCH	73	13.770	0.1009	Yes
6	NFKBIA	116	12.486	0.1128	Yes
7	ARF6	219	10.345	0.1197	Yes
8	GBF1	273	9.723	0.1281	Yes
9	CD4	297	9.537	0.1376	Yes
10	ETS1	300	9.524	0.1481	Yes
11	YWHAZ	325	9.321	0.1574	Yes
12	MEF2D	333	9.231	0.1674	Yes
13	DAPP1	361	9.005	0.1762	Yes
14	JUNB	376	8.916	0.1855	Yes
15	YWHAE	396	8.835	0.1944	Yes
16	VAV2	421	8.556	0.2029	Yes
17	TNFAIP3	474	8.304	0.2097	Yes
18	PLCG1	539	7.963	0.2156	Yes
19	EGR1	548	7.925	0.2241	Yes
20	GGA3	552	7.908	0.2328	Yes
21	PRKACA	580	7.756	0.2402	Yes
22	VAV1	628	7.582	0.2464	Yes
23	CSNK2A1	727	7.148	0.2499	Yes
24	RAF1	819	6.824	0.2533	Yes
25	NFATC1	826	6.800	0.2606	Yes
26	CARD11	836	6.773	0.2677	Yes
27	CDKN1B	888	6.624	0.2728	Yes
28	RELA	916	6.549	0.2788	Yes
29	PPP3CB	991	6.360	0.2825	Yes
30	TBC1D4	1027	6.281	0.2879	Yes
31	ITK	1091	6.101	0.2918	Yes
32	IKBKG	1106	6.072	0.2979	Yes
33	TSC1	1140	6.004	0.3031	Yes
34	BCL2	1151	5.973	0.3093	Yes
35	NFATC3	1178	5.913	0.3147	Yes
36	PTEN	1189	5.873	0.3208	Yes
37	SYK	1212	5.837	0.3262	Yes
38	CSK	1223	5.821	0.3323	Yes
39	TSC2	1289	5.637	0.3356	Yes
40	AKT2	1306	5.599	0.3411	Yes
41	AP2M1	1343	5.518	0.3455	Yes
42	CD79B	1433	5.349	0.3474	Yes
43	NFKB2	1444	5.315	0.3529	Yes
44	NUP214	1449	5.310	0.3586	Yes
45	FBXW11	1563	5.105	0.3591	Yes
46	FKBP1A	1567	5.097	0.3646	Yes
47	CAMK4	1688	4.913	0.3646	Yes
48	PAG1	1698	4.900	0.3696	Yes
49	RELB	1827	4.711	0.3690	Yes
50	EEF2	1841	4.691	0.3736	Yes
51	CBLB	1885	4.615	0.3768	Yes
52	PPP5C	1912	4.582	0.3807	Yes
53	MAP3K14	1956	4.529	0.3837	Yes
54	MAPK3	1966	4.511	0.3884	Yes
55	EIF4E	2088	4.365	0.3876	Yes
56	PDPK1	2170	4.258	0.3887	Yes
57	CREBBP	2209	4.217	0.3916	Yes
58	MAPKAP1	2213	4.210	0.3962	Yes
59	MAP3K1	2233	4.194	0.4000	Yes
60	NR4A1	2240	4.181	0.4043	Yes
61	CLTA	2273	4.143	0.4075	Yes
62	FKBP8	2303	4.111	0.4107	Yes
63	JUN	2591	3.817	0.4018	Yes
64	SHC1	2716	3.694	0.4002	Yes
65	MALT1	2770	3.638	0.4018	Yes
66	BCL10	2773	3.637	0.4058	Yes
67	TIAM1	2834	3.585	0.4070	Yes
68	E2F1	2859	3.556	0.4099	Yes
69	PIK3CA	2870	3.541	0.4133	Yes
70	ATM	2892	3.523	0.4163	Yes
71	PRKDC	2950	3.473	0.4175	Yes
72	GSK3B	2980	3.451	0.4200	Yes
73	CALM3	3006	3.431	0.4227	Yes
74	PTPRC	3046	3.398	0.4247	Yes
75	MAPK14	3074	3.368	0.4272	Yes
76	ZAP70	3141	3.317	0.4279	Yes
77	IBTK	3161	3.298	0.4307	Yes
78	CLTB	3192	3.267	0.4329	Yes
79	DOK1	3306	3.173	0.4313	Yes
80	RPS6KB1	3354	3.133	0.4326	Yes
81	SOS1	3360	3.127	0.4359	Yes
82	MDM2	3409	3.096	0.4371	Yes
83	ARF5	3501	3.020	0.4363	Yes
84	ARFGAP1	3521	3.003	0.4387	Yes
85	DGKA	3551	2.979	0.4407	Yes
86	BAD	3655	2.905	0.4392	Yes
87	ARF1	3666	2.899	0.4420	Yes
88	CTLA4	3798	2.805	0.4391	Yes
89	AKT1	3802	2.803	0.4421	Yes
90	AKT3	3957	2.670	0.4380	No
91	TBX21	4197	2.508	0.4298	No
92	ERC1	4304	2.438	0.4276	No
93	NFKBIB	4385	2.393	0.4266	No
94	PTPN1	4451	2.352	0.4262	No
95	PTPN6	4545	2.295	0.4245	No
96	BIRC2	4594	2.264	0.4248	No
97	SRC	4632	2.239	0.4256	No
98	HSP90AA1	4681	2.210	0.4258	No
99	ARRB2	4687	2.206	0.4281	No
100	YES1	4731	2.186	0.4285	No
101	EP300	4765	2.162	0.4294	No
102	ARHGEF7	4847	2.125	0.4281	No
103	ELK1	4900	2.097	0.4280	No
104	COPA	5347	1.853	0.4095	No
105	FOXP3	5609	1.722	0.3994	No
106	GSK3A	5701	1.683	0.3971	No
107	CYLD	5710	1.680	0.3986	No
108	PIK3R1	5770	1.654	0.3978	No
109	CSF2	5829	1.624	0.3969	No
110	ARHGEF6	6013	1.536	0.3902	No
111	NRAS	6347	1.384	0.3764	No
112	YWHAH	6354	1.382	0.3777	No
113	AP2A1	6415	1.354	0.3764	No
114	PRKCQ	6476	1.323	0.3751	No
115	FYN	6571	1.275	0.3722	No
116	TRAF6	6611	1.253	0.3718	No
117	FOS	6777	1.183	0.3656	No
118	PRKCD	6849	1.149	0.3636	No
119	CHUK	6991	1.084	0.3583	No
120	PRKCH	7283	0.959	0.3460	No
121	IL4	7504	0.867	0.3368	No
122	FOSL1	7749	0.760	0.3264	No
123	RHOA	7991	0.666	0.3161	No
124	POU2F1	7999	0.663	0.3165	No
125	PIM1	8068	0.635	0.3141	No
126	PRKAB1	8148	0.596	0.3111	No
127	PLEKHA1	8993	0.235	0.2725	No
128	REL	9035	0.218	0.2709	No
129	MAP3K8	10010	-0.225	0.2263	No
130	PTGS2	10878	-0.540	0.1870	No
131	CD19	10959	-0.570	0.1840	No
132	MKNK1	11007	-0.582	0.1825	No
133	PLD2	11148	-0.637	0.1767	No
134	EGR4	11183	-0.648	0.1759	No
135	CD40LG	11288	-0.678	0.1718	No
136	RPS6	11490	-0.745	0.1634	No
137	BTK	12025	-0.929	0.1399	No
138	BCL3	12040	-0.931	0.1403	No
139	CD22	12622	-1.103	0.1148	No
140	GOSR2	12823	-1.165	0.1069	No
141	IRF4	12943	-1.197	0.1027	No
142	IRS1	13166	-1.265	0.0939	No
143	PLEKHA2	13207	-1.276	0.0935	No
144	MAP2K1	13318	-1.307	0.0899	No
145	IL3	13399	-1.333	0.0877	No
146	TNF	13449	-1.346	0.0869	No
147	AKT1S1	13535	-1.374	0.0846	No
148	AKAP5	13585	-1.389	0.0839	No
149	PRKCZ	13684	-1.423	0.0809	No
150	EIF4G1	14061	-1.526	0.0653	No
151	INSR	14072	-1.529	0.0666	No
152	CASP3	14102	-1.535	0.0670	No
153	HCK	14105	-1.536	0.0686	No
154	POU2F2	14450	-1.632	0.0546	No
155	MAPK9	14521	-1.654	0.0532	No
156	PPP2R5D	14684	-1.704	0.0476	No
157	CALM2	14820	-1.748	0.0434	No
158	CD79A	15127	-1.844	0.0313	No
159	KPNA1	15324	-1.901	0.0244	No
160	ARFIP2	15859	-2.082	0.0022	No
161	BLNK	15915	-2.099	0.0020	No
162	PRKCE	16103	-2.152	-0.0042	No
163	CASP9	16271	-2.209	-0.0094	No
164	IFNG	16549	-2.307	-0.0196	No
165	RAP1A	16633	-2.333	-0.0208	No
166	RASA1	16898	-2.430	-0.0303	No
167	RHEB	16939	-2.445	-0.0294	No
168	RIPK2	16962	-2.453	-0.0277	No
169	FASLG	17031	-2.476	-0.0281	No
170	SLC2A4	17567	-2.667	-0.0497	No
171	CD72	17655	-2.708	-0.0507	No
172	SFN	18116	-2.905	-0.0686	No
173	EIF4EBP1	18133	-2.908	-0.0661	No
174	HRAS	18182	-2.929	-0.0651	No
175	CDKN1A	18276	-2.964	-0.0660	No
176	MAF	18485	-3.064	-0.0722	No
177	SLC3A2	18581	-3.111	-0.0731	No
178	PPP3CA	18699	-3.178	-0.0749	No
179	MAP3K7	18867	-3.272	-0.0790	No
180	RNF128	18899	-3.297	-0.0767	No
181	CALM1	18993	-3.349	-0.0773	No
182	KPNB1	19033	-3.372	-0.0753	No
183	PDE3B	19067	-3.392	-0.0731	No
184	CDKN2A	19143	-3.446	-0.0727	No
185	MAPK8	19156	-3.453	-0.0694	No
186	PPARG	19187	-3.475	-0.0669	No
187	XPO1	19211	-3.485	-0.0641	No
188	YWHAB	19433	-3.637	-0.0702	No
189	NFATC2	19548	-3.725	-0.0713	No
190	IKBKB	19586	-3.755	-0.0688	No
191	IL2RA	19843	-3.987	-0.0761	No
192	INPPL1	19844	-3.988	-0.0717	No
193	PLCG2	19865	-4.009	-0.0682	No
194	GATA3	19901	-4.038	-0.0653	No
195	FGR	20050	-4.194	-0.0674	No
196	EIF4A1	20054	-4.197	-0.0629	No
197	UBE2D3	20226	-4.387	-0.0658	No
198	KRAS	20270	-4.421	-0.0629	No
199	RAC1	20404	-4.590	-0.0639	No
200	MAPK1	20477	-4.696	-0.0620	No
201	PTPRK	20543	-4.769	-0.0597	No
202	YWHAG	20590	-4.829	-0.0564	No
203	SH3BP5	20626	-4.874	-0.0526	No
204	GRB2	20842	-5.251	-0.0566	No
205	FRAP1	20899	-5.323	-0.0533	No
206	BLK	20922	-5.356	-0.0483	No
207	CDK4	21020	-5.528	-0.0466	No
208	YWHAQ	21137	-5.795	-0.0455	No
209	RAN	21154	-5.842	-0.0397	No
210	NFKB1	21220	-6.043	-0.0360	No
211	CAMK2G	21269	-6.196	-0.0313	No
212	TP53	21287	-6.255	-0.0251	No
213	PRKCA	21377	-6.512	-0.0220	No
214	PPP3CC	21439	-6.721	-0.0173	No
215	FCGR2B	21564	-7.183	-0.0150	No
216	CSNK1A1	21599	-7.335	-0.0084	No
217	IL5	21945	-21.856	0.0001	No